Type 1 Diabetes is a complex autoimmune condition characterized by immune-mediated damage to pancreatic beta cells, resulting in impaired glucose regulation.
Emerging evidence suggests that gut-derived inflammatory signaling and neuro-immune dysregulation may influence autoimmune activity and regulatory control in susceptible individuals.

 

CIAR addresses:

•  Interpreting immune-mediated beta-cell stress within a systems framework

• Understanding gut-immune contributions to autoimmune susceptibility

• Examining pancreatic inflammatory signaling in metabolic dysregulation

• Exploring neuro-immune reflexes involved in immune regulation

This framework supports scientific understanding of disease mechanisms and informs future research directions in immune-metabolic regulations.